Talk:Deep brain stimulation

Nucleus basalis / Basal nucleus of Meynert

The image shows the electrode in the Basal nucleus of Meynert but the article only mentions the globus pallidus internus, thalamus, subthalamic nucleus and the pedunculopontine nucleus as targets. Why? Abductive (reasoning) 03:15, 28 November 2019 (UTC)

@Abductive: Because the scholarly source that article text is based on mentions only those targets. We need to either find another good image or another reliable secondary source that bridges the gap between image and text. Perhaps you know where to find one or the other? --RexxS (talk) 14:25, 28 November 2019 (UTC)

It seems to be in the trial phase for Lewy Body Dementia. I am removing it as it is not a common target and the sourcing is primary, per WP:MEDRS. Abductive (reasoning) 22:40, 28 November 2019 (UTC)

Development and/or History of the Procedure?

On other non-stub medical procedure Wikipedia pages, it is common-place to find the history and/or the development of said procedure (e.g., Lobotomy#History). Perhaps an inclusion of such a section would be relevant to this article as well. Sink Cat (talk) 03:40, 20 February 2023 (UTC)

Here you go:

• Schwalb JM, Hamani C (January 2008). "The history and future of deep brain stimulation" (PDF). Neurotherapeutics. 5 (1): 3–13. doi:10.1016/j.nurt.2007.11.003. PMID 18164479.
• Pycroft L, Stein J, Aziz T (2018). "Deep brain stimulation: An overview of history, methods, and future developments". Brain Neurosci Adv. 2: 2398212818816017. doi:10.1177/2398212818816017. PMC 7058209. PMID 32166163.

SandyGeorgia (Talk) 03:49, 20 February 2023 (UTC)

Original research and tone

We need to be extremely careful with original research and encyclopedic tone. I am going to be putting in a little work on this article over the next week. I will post an edit summary here when done. I would ask anyone editing this article to carefully review WP:MEDMOS. I enjoy sandwiches (talk) 19:54, 1 December 2024 (UTC)

Proposed merge of Adaptive deep brain stimulation into Deep brain stimulation

Programming feature, not a new technology. Most of "adaptive DBS" article 1) doesn't qualify for medmos or 2) is redundant to "DBS" article I enjoy sandwiches (talk) 23:12, 25 January 2025 (UTC)

Support; minor tweak that grabs a few headlines with a new name to aid promotion - part of the continuous improvement of the technique. There's also a lot of overlap, with most of Adaptive deep brain stimulation just describing DBS. Klbrain (talk) 11:18, 1 February 2025 (UTC)

Suicide risk

The largest and most recent studies generally indicate a higher suicide and depression risk with DBS, particularly with treatment of the STN:

• Suicide and suicide attempts after subthalamic nucleus stimulation in Parkinson's disease: a systematic review and meta-analysis - PubMed
• Parkinson’s Disease-Related Risk of Suicide and Effect of Deep Brain Stimulation: Meta-Analysis - PubMed

Note that the latter of these is from Hindawi, which is cited as a questionable journal on Citewatch, but its results are nearly identical to those of the first study.

There is one retrospective cohort study that contradicts these two:

https://journals.sagepub.com/doi/full/10.3233/JPD-225049

However, they compared people within first 10 years of PD diagnosis to people within first 10 years of DBS. These aren't equivalent populations (UPDRS I vs UPDRS II-IV) - this is a loophole large enough to drive a truck through. Basically a dry lab. The authors are all affiliated with DBS manufacturers - RD provides consulting for Medtronic, SGO's fellowship is funded by Medtronic, Abbott, and Boston Scientific, and OK is a full-time employee of Neurocrine.

Similar issues occur throughout this article and I would advise future editors to be hypervigilant about paid editors for the device. I am working on a rewrite in my sandbox and will submit it as soon as possible. I enjoy sandwiches (talk) 18:23, 4 March 2025 (UTC)